Algonot products seek to provide:
Balanced Body and Mind
Free Radical Scavengers
Immune System Modulators
Prevention & Recovery
Dr. Theoharis Theoharides (Dr. Theo), MS, PhD, MD, FAAAAI, is Professor of Pharmacology, Internal Medicine and Biochemistry and Director of the Molecular Immuno-pharmacology and Drug Discovery Laboratory at Tufts University School of Medicine. He has done over 20 years of research into mast cells and brain inflammation and published 300 papers.
His research has shown that mast cells are one of the master regulators of the immune system, directing immune system response and controlling inflammation. Dysfunction of mast cells has being found to be the source of many autoimmune diseases and conditions. In the rising tide of modern day diseases and ailments there is a single type of cell in the body that affects almost all of them, from autism to ADHD, cancer to Alzheimer’s, fibromialgia to Parkinson’s, and more – mast cells – and Dr. Theoharides’ research is providing new targets for treatment.
What are Mast Cells?
Recent research has proved mast cells act as orchestra conductors in the immune system, controlling reactions from allergies to inflammation, and a wide range of other immune regulation functions. Their effect is wide ranging, influencing attacks on viruses and bacteria, intestinal movement, gut bacteria, and adrenal and pituitary function.
If mast cells get overwhelmed, they can “degranulate” (think explode), releasing too many immune molecules at once. This is needed for a major immune response like a traumatic injury, but if this happens too much, a chain reaction starts that leads to an autoimmune-like response.
Once this chain reaction starts, the protective gut–blood and blood–brain barriers are quickly broken down. Once the blood–brain barrier is penetrated, the immune system of the brain, microglia, reacts. This interaction between the mast cells and the microglia is a Brain immune Storm.
Dr. Theoharides has developed a natural way to calm mast cell activation. The flavonoid Luteolin has been shown by multiple researchers to stop the mast cell activation chain reaction. Since Dr. Theoharides could not find any supplements with pure sources of Luteolin, and since Luteolin is hard for the body to absorb, he developed a supplement called NeuroProtek, produced by Algonot.
How might NeuroProtek® be helpful?
The active ingredients in NeuroProtek: Luteolin, Rutin, and Quercetin were selected to provide the maximum antioxidant, anti-inflammatory, mast cell inhibitory, and neuro-protective effects.
The peptide neurotensin that can be released from the gut or the brain, and was recently shown to be increased in the serum of autistic children, can stimulate mast cells to release molecules that disrupt the barriers. Luteolin acts mostly in the brain to reduce barrier disruption and brain inflammation, while rutin does so in the gut. Quercetin mostly inhibits mast cells and is preferentially metabolized in the liver to permit Luteolin to act.
Resources for Questions about NeuroProtek
The benefits of NeuroProtek in reducing inflammation, overactive immune function and allergic response, well known to those in the autism community, may also benefit children with a diagnosis of PANS or PANDAS. The Thinking Moms’ Revolution is grateful to Algonot for generously sponsoring our upcoming FREE online conference PANS/PANDAS: Comprehensive and Novel Treatment Approaches to Heal the Microbiome on April 5th from 9 a.m.–5 p.m. EDT.
Register for the conference HERE.
~ The Thinking Moms’ Revolution